CJC-1295 No DAC 10mg

CJC-1295 No DAC 10mg from Revive Peptides is a high-quality research peptide supplied as a lyophilized (freeze-dried) powder for laboratory use. Also known as Modified GRF 1-29, it is one of the most widely studied growth hormone-releasing hormone (GHRH) analogs, valued by researchers for its stability and its short, pulse-like activity profile.

What Is CJC-1295 No DAC?

CJC-1295 No DAC is a modified version of the first 29 amino acids of natural GHRH, the shortest fragment that keeps full biological activity. Four amino acid substitutions, at positions 2 (D-Ala), 8 (Gln), 15 (Ala), and 27 (Leu), protect the peptide from rapid enzymatic breakdown and oxidation, giving it a longer half-life than native GHRH (roughly 30 minutes versus a few minutes) while still acting on the same GHRH receptors in the pituitary gland.

Because it does not include the Drug Affinity Complex, the peptide does not bind to albumin in the bloodstream. The result is a short burst of activity that closely mimics the body’s natural, pulsatile pattern of growth hormone secretion, which is why it is a common choice in endocrine and metabolic research models.

CJC-1295 No DAC vs. CJC-1295 DAC

The key difference between the two forms is duration of action. CJC-1295 DAC carries a lysine-linked maleimide group that binds to serum albumin, extending its half-life to several days. In a published clinical study, the DAC version produced sustained elevations of growth hormone and IGF-1 lasting days after a single administration (Teichman et al., 2006).

The no-DAC form works the other way: a brief, sharp signal that clears quickly. Researchers studying natural GH pulses, timing, and receptor sensitivity often prefer the no-DAC form because it avoids the continuous “GH bleed” associated with long-acting analogs.

Research Applications of CJC-1295 No DAC

This peptide is studied in a wide range of laboratory research involving:

• Pulsatile growth hormone release and GHRH receptor signalling
• IGF-1 regulation and downstream endocrine pathways
• Body composition, protein synthesis, and metabolic function
• Recovery, tissue repair, and sleep-related GH secretion
• Age-related decline in the growth hormone axis

Its short duration of action gives researchers precise control over timing, making it easier to compare single pulses, repeated pulses, and combination protocols within the same study design.

Pairing with GHRPs such as Ipamorelin

Mod GRF 1-29 is frequently studied alongside growth hormone-releasing peptides (GHRPs) such as Ipamorelin 10mg and GHRP-2 10mg. GHRH analogs and GHRPs act on different receptors, and research suggests the combination produces a stronger GH pulse than either compound alone. For convenience, we also carry a pre-mixed CJC-1295 No DAC + Ipamorelin 5mg blend.

Product Specifications

Storage and Handling

Store unopened vials of lyophilized powder in a cool, dry place away from light. For long-term storage, keep at -20°C; for short-term storage, refrigerate at 2-8°C. Once reconstituted with bacteriostatic water, keep the vial refrigerated and avoid repeated freeze-thaw cycles. Our peptide calculator can help with reconstitution math for laboratory protocols.

Lab Testing and Certificate of Analysis

Every batch at Revive Peptides is sent for independent third-party testing. The Certificate of Analysis for CJC-1295 No DAC 10mg is in progress and will be posted on our Lab Results page as soon as it is available.

Buy CJC-1295 No DAC in Canada

Revive Peptides ships across Canada with fast, discreet, tracked delivery. If you are building a growth hormone research protocol, you may also be interested in Sermorelin 10mg, another GHRH analog, or Tesamorelin 10mg.

Disclaimer: This product is sold strictly for laboratory research purposes. It is not a drug, food, or cosmetic, and is not intended for human or animal consumption, or to diagnose, treat, cure, or prevent any disease.